From a design perspective, clerestory windows add visual interest and architectural character to a building's facade. Their placement high on walls creates a sense of height and spaciousness, making rooms feel larger and more open. Clerestory windows can also be used to highlight specific architectural features or draw attention to unique design elements, serving as focal points within a space.

In residential architecture, clerestory windows are often incorporated into modern house designs to maximize natural light and ventilation. A clerestory house design typically features one or more rows of clerestory windows along the upper walls of living spaces, such as the living room, dining area, or master bedroom. This design approach not only enhances the aesthetic appeal of the home but also improves comfort and livability for occupants.